OcrV1, Main, Exploration, bibRecord, 000A78

Loss of otolith function with age is associated with increased postural sway measures

Identifieur interne : 000A78 ( Main/Exploration ); précédent : 000A77; suivant : 000A79

Loss of otolith function with age is associated with increased postural sway measures

Auteurs : Jorge M. Serrador [États-Unis, Irlande (pays)] ; Lewis A. Lipsitz [États-Unis] ; Gosala S. Gopalakrishnan [États-Unis] ; F. Owen Black [États-Unis] ; Scott J. Wood [États-Unis]

Source :

Neuroscience letters [ 0304-3940 ] ; 2009.

RBID : Pascal:09-0445653

Descripteurs français

Pascal (Inist)
- Otolithe, Age, Sénescence, Sexe.

English descriptors

KwdEn :
- Age, Otolith, Senescence, Sex.

Abstract

Loss of balance and increased fall risk is a common problem associated with aging. Changes in vestibular function occur with aging but the contribution of reduced vestibular otolith function to fall risk remains unknown. We examined a population of 151 healthy individuals (aged 21-93) for both balance (sway measures) and ocular counter-rolling (OCR) function. We assessed balance function with eyes open and closed on a firm surface, eyes open and closed on a foam surface and OCR during ±20 degree roll tilt at 0.005 Hz. Subjects demonstrated a significant age-related reduction in OCR and increase in postural sway. The effect of age on OCR was greater in females than males. The reduction in OCR was strongly correlated with the mediolateral measures of sway with eyes closed. This correlation was also present in the elderly group alone, suggesting that aging alone does not account for this effect. OCR decreased linearly with age and at a greater rate in females than males. This loss of vestibular otolith-ocular function is associated with increased mediolateral measures of sway which have been shown to be related to increased risk of falls. These data suggest a role for loss of otolith function in contributing to fall risk in the elderly. Further prospective, longitudinal studies are necessary to confirm these findings.

Affiliations:

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Le document en format XML

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<series><title level="j" type="main">Neuroscience letters</title>
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<term>Age</term>
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<front><div type="abstract" xml:lang="en">Loss of balance and increased fall risk is a common problem associated with aging. Changes in vestibular function occur with aging but the contribution of reduced vestibular otolith function to fall risk remains unknown. We examined a population of 151 healthy individuals (aged 21-93) for both balance (sway measures) and ocular counter-rolling (OCR) function. We assessed balance function with eyes open and closed on a firm surface, eyes open and closed on a foam surface and OCR during ±20 degree roll tilt at 0.005 Hz. Subjects demonstrated a significant age-related reduction in OCR and increase in postural sway. The effect of age on OCR was greater in females than males. The reduction in OCR was strongly correlated with the mediolateral measures of sway with eyes closed. This correlation was also present in the elderly group alone, suggesting that aging alone does not account for this effect. OCR decreased linearly with age and at a greater rate in females than males. This loss of vestibular otolith-ocular function is associated with increased mediolateral measures of sway which have been shown to be related to increased risk of falls. These data suggest a role for loss of otolith function in contributing to fall risk in the elderly. Further prospective, longitudinal studies are necessary to confirm these findings.</div>
</front>
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Loss of otolith function with age is associated with increased postural sway measures

Loss of otolith function with age is associated with increased postural sway measures

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri